Leather and vinyl chairs are far easier to wipe clean with a mild detergent. If germs are a major concern, it is hard to beat the benefits of a smooth surface. Leather is more durable than vinyl but overall, they both work well. However, the downside is they tend to be more expensive and can be a little cold at first when you sit. Which is best for a particular individual is a judgement call based on personal preference.
MPN: LEE10050$1.69 / EA
MPN: IDEVZ00323$88.34 / EA
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MPN: OXF04635$14.49 / ST
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MPN: SAN2211379$20.04 / PK
MPN: DIXX60300$2.91 / EA
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MPN: STCMXT105MMHQ$22.98 / EA