Leather and vinyl chairs are far easier to wipe clean with a mild detergent. If germs are a major concern, it is hard to beat the benefits of a smooth surface. Leather is more durable than vinyl but overall, they both work well. However, the downside is they tend to be more expensive and can be a little cold at first when you sit. Which is best for a particular individual is a judgement call based on personal preference.
MPN: CNMPGI2200XLBK$56.86 / EA
MPN: NSN2555135$724.89 / BX
MPN: SMD81724$7.1 / EA
MPN: SMD67600$6.94 / PK
MPN: DLLXMX5D$114.84 / EA
MPN: LLR62008102$590.44 / EA
MPN: PFX85363$75.84 / BX
MPN: EGO40806$36.33 / EA
MPN: LLR23100073$488.36 / EA
MPN: KFI30R917SL38LE$465.61 / EA
MPN: BSHHUS001NE$473.43 / EA
MPN: SMD13084$53.09 / BX